New quinolones 3, 6 and 9 mmelated to either a 5-raembered or a 6-membered lactone were designed as hybrids of antibacterial 4-quinolones and antitumor epipodophyllotoxin derivatives. They were synthezised using ethyl 2-ethenyl-4-hydroxy-l,2-dihydroquinoline-3-carboxylate 2 as a key intermediate.
Acid anilides: XII. The preparation of 4- and 5-hydroxyalkananilides from γ- and δ-lactones
✍ Scribed by A. P. de Jonge; B. van der Ven
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 258 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0165-0513
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