𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hypervalent iodine oxidation of 5-keto acids and 4,6-diketo acids with [hydroxy(tosyloxy)iodo]benzene: Synthesis of keto-γ-lactones and diketo-δ-lactones

✍ Scribed by R.M. Moriarty; R.K. Vaid; T.E. Hopkins; B.K. Vaid; O. Prakash†


Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
203 KB
Volume
31
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


Hypervalent iodine oxidation of 5-ketoacids, using [hydroxy(tosyloxy)iodo]benzene in dichloromethane under refluxing conditions yielded keto-y-lactones.

Oxidation of 4,6-diketoacids with [hydroxy(tosyloxy)iodolbenzene at room temperature afforded the corresponding diketo-&lactones.