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Accelerated α-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells

✍ Scribed by Takafumi Hasegawa; Michiko Matsuzaki; Atsushi Takeda; Akio Kikuchi; Hirotoshi Akita; George Perry; Mark A Smith; Yasuto Itoyama

Book ID
113499712
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
531 KB
Volume
1013
Category
Article
ISSN
0006-8993

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✍ Cristina Gómez-Santos; Isidre Ferrer; Antonio F. Santidrián; Marta Barrachina; J 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 523 KB

## Abstract Free cytoplasmic dopamine may be involved in the genesis of neuronal degeneration in Parkinson's disease and other such diseases. We used SH‐SY5Y human neuroblastoma cells to study the effect of dopamine on cell death, activation of stress‐induced pathways, and expression of α‐synuclein