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α-Synuclein overexpression during manganese-induced apoptosis in SH-SY5Y neuroblastoma cells

✍ Scribed by Yan Li; Liguang Sun; Tongjian Cai; Ying Zhang; Shijie Lv; Yu Wang; Liping Ye


Book ID
116327037
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
523 KB
Volume
81
Category
Article
ISSN
0361-9230

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✍ Cristina Gómez-Santos; Isidre Ferrer; Antonio F. Santidrián; Marta Barrachina; J 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 523 KB

## Abstract Free cytoplasmic dopamine may be involved in the genesis of neuronal degeneration in Parkinson's disease and other such diseases. We used SH‐SY5Y human neuroblastoma cells to study the effect of dopamine on cell death, activation of stress‐induced pathways, and expression of α‐synuclein