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Absolute configuration of curacin A, a novel antimitotic agent from the tropical marine cyanobacterium Lyngbya majuscula

โœ Scribed by Dale G. Nagle; Robin S. Geralds; Hye-Dong Yoo; William H. Gerwick; Tae-Seong Kim; Mitch Nambu; James D. White

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
226 KB
Volume
36
Category
Article
ISSN
0040-4039

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The title compound (XV) is synthesized via highly stereoselective allylation of the aldehyde (VIII), Wittig reaction of the phosphonium salt (XI) with the aldehyde (XII), and condensation of the amino thiol (XIII) with the acid (XIV). -(ONODA, T.;