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ChemInform Abstract: Curacin D, an Antimitotic Agent from the Marine Cyanobacterium Lyngbya majuscula.

โœ Scribed by Brian Marquez; Pascal Verdier-Pinard; Ernest Hamel; William H. Gerwick

Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthetic Study on
ChemInform Abstract: Synthetic Study on Curacin A: A Novel Antimitotic Agent from the Cyanobacterium Lyngbya majuscula.
โœ T. ONODA; R. SHIRAI; Y. KOISO; S. IWASAKI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 34 KB ๐Ÿ‘ 2 views

The title compound (XV) is synthesized via highly stereoselective allylation of the aldehyde (VIII), Wittig reaction of the phosphonium salt (XI) with the aldehyde (XII), and condensation of the amino thiol (XIII) with the acid (XIV). -(ONODA, T.;