ChemInform Abstract: Synthetic Study on Curacin A: A Novel Antimitotic Agent from the Cyanobacterium Lyngbya majuscula.

✍ Scribed by T. ONODA; R. SHIRAI; Y. KOISO; S. IWASAKI

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 34 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199712244

✦ Synopsis

The title compound (XV) is synthesized via highly stereoselective allylation of the aldehyde (VIII), Wittig reaction of the phosphonium salt (XI) with the aldehyde (XII), and condensation of the amino thiol (XIII) with the acid (XIV). -(ONODA, T.;