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Absence of the apolipoprotein E ε4 allele is associated with working memory impairment in Parkinson's disease

✍ Scribed by Alexander I. Tröster; Julie A. Fields; Anthony M. Paolo; William C. Koller


Book ID
119302001
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
112 KB
Volume
248
Category
Article
ISSN
0022-510X

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Apolipoprotein E ε4 allele is associated
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## Abstract We investigated the association between apolipoprotein E (__APOE__) alleles and genotypes and Parkinson disease (PD) in 229 unrelated Mexican Mestizo PD patients and 229 controls. Results showed that both __APOE__‐ε4 allele and __APOE__ ε4/ε3 genotype are associated with PD (OR = 1.736,

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✍ K. W. Kim; J. C. Youn; J. H. Jhoo; D. Y. Lee; K. U. Lee; J. H. Lee; J. I. Woo 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 63 KB 👁 1 views

## Objectives: The aim of this study was to examine whether the apoe epsilon 4 allele also confers a risk for the cognitive impairment in normal aging. ## Methods: We administered all the eight neuropsychological tests from the cerad neuropsychological battery to the cvd-free, community-dwelling