𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Absence of somatic alterations of the EB1 gene adenomatous polyposis coli-associated protein in human sporadic colorectal cancers

✍ Scribed by Jaïs, P; Sabourin, J-C; Bombled, J; Rougier, P; Lasser, P; Duvillard, P; Bénard, J; Bressac-de Paillerets, B


Book ID
109838678
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
851 KB
Volume
78
Category
Article
ISSN
0007-0920

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Mutation analysis of the adenomatous pol
✍ Clara Ruiz-Ponte; Ana Vega; Angel Carracedo; Francisco Barros 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 26 KB 👁 2 views

Germline mutations in the tumor-suppresor APC gene are associated with hereditary familial adenomatous polyposis (FAP) and somatic mutations are common in sporadic colorectal cancer. In this study, we report the identification of three novel germline mutations: 1682-1683insA, 3252-3253insAT, 3544A>T

Mutations of the adenomatous polyposis c
✍ Kazuo Yashima; Shouji Nakamori; Yoshinori Murakami; Akio Yamaguchi; Kenshi Hayas 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 678 KB

## Abstract We analyzed the adenomatous polyposis coli (__APC__) tumorsuppressor gene as one of the possible genes mutated in human pancreatic carcinomas. DNAs from 39 surgical specimens were subjected to single‐strand conformation polymorphism analysis of polymerase chain reaction products and the

Hypermethylation of the APC (adenomatous
✍ Mikko O. Hiltunen; Leena Alhonen; Jari Koistinaho; Sanna Myöhänen; Matti Pääkkön 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 206 KB 👁 2 views

Germline mutations of the putative tumor suppressor gene APC are associated in high frequency with the familial adenomatous polyposis, predisposing the patients to colorectal neoplasia. Similarly, sequence analyses have revealed that in more than half of patients with sporadic colorectal carcinoma o

Infrequent somatic mutation of the adeno
✍ Kazuhiko Otori; Motoko Konishi; Kenji Sugiyama; Takahiro Hasebe; Tadakazu Shimod 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 99 KB 👁 2 views

## Background: The authors examined somatic mutations of the adenomatous polyposis coli (apc) gene in 84 human aberrant crypt foci (acf) to determine whether apc gene mutations were involved in the histologic progression of acf. ## Methods: Mutation cluster regions of the apc gene were subjected

Deletion analysis of the adenomatous pol
✍ Alexander O. Vortmeyer; Theodora Stavrou; Dena Selby; Guang Li; Robert J. Weil; 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 263 KB 👁 3 views

## BACKGROUND. Medulloblastomas can occur sporadically or may be associated with hereditary tumor syndromes including familial adenomatous polyposis (FAP) and nevoid basal cell carcinoma syndrome (NBCCS). ## METHODS. The authors performed a retrospective analysis for allelic deletion of the adeno