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A2A adenosine receptor agonists for the treatment of asthma?

✍ Scribed by G. Trifoglio Benfatto; R. Polosa


Book ID
110886596
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
59 KB
Volume
63
Category
Article
ISSN
0105-4538

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CoMFA Study on Adenosine A2A Receptor Ag
✍ Doytchinova, Irini ;Valkova, Iva ;Natcheva, Roumiana πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 205 KB πŸ‘ 2 views

A step-wise CoMFA-based procedure was applied to a series of 51 C2-oxyadenosines in order to select the most predictive conformation for binding to A 2A adenosine receptor. The highest correlation and predictive power was found for conformers with the side chain at the 2position oriented in the dire