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A validated liquid chromatography tandem mass spectrometry method for simultaneous determination of pioglitazone, hydroxypioglitazone, and ketopioglitazone in human plasma and its application to a clinical study

✍ Scribed by Kawaguchi-Suzuki, Marina; Bril, Fernando; Sanchez, Paola Portillo; Cusi, Kenneth; Frye, Reginald F.

Book ID
126265194
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
399 KB
Volume
969
Category
Article
ISSN
1873-376X

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## Abstract A simple, sensitive and specific liquid chromatography‐tandem mass spectrometry method for the quantification of bromopride I in human plasma is presented. Sample preparation consisted of the addition of procainamide II as the internal standard, liquid‐liquid extraction in alkaline cond