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Determination of tamsulosin in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study

โœ Scribed by Chang-Ik Choi; Hye-In Lee; Jung-Woo Bae; Yun-Jeong Lee; Ji-Yeong Byeon; Choon-Gon Jang; Seok-Yong Lee


Book ID
119289325
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
401 KB
Volume
909
Category
Article
ISSN
1873-376X

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## Abstract A rapid and sensitive LC/MS/MS assay was developed and validated for the determination of clopidogrel in human plasma. Clopidogrel was extracted by single liquidโ€“liquid extraction with pentane, and chromatographic separations were achieved on a C~18~ column. The method was validated to