✦ LIBER ✦

A study of the oncogenicity of adenovirus type 2 transformed rat embbyo cells

✍ Scribed by Lesley M. J. Harwood; P. H. Gallimore

Publisher: John Wiley and Sons
Year: 1975
Tongue: French
Weight: 711 KB
Volume: 16
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910160317

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Rat embryo cells were transformed by adenovirus type 2 at different multiplicities of infection. The oncogenic potential of the resulting transformed lines varied considerably but a relationship was found to exist between transforming virus dose and oncogenicity of the resulting transformed lines. Possible reasons for the considerable variation in oncogenicity of the transformed lines are discussed, giving particular consideration to cellular antigenicity and recent molecular biology studies of adenovirus type 2 transformed cell lines.

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