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A study of chemical carcinogenesis 4. Synthesis of the carbon-14 labelled carcinogens 5-methylchrysene, 2-methyl-aniline and 3-methyl-2-naphthylamine

✍ Scribed by Louis Weiss; Myrna Loy; Stephen S. Hecht; Dietrich Hoffmann

Publisher
John Wiley and Sons
Year
1978
Tongue
French
Weight
503 KB
Volume
14
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Procedures were developed for synthesis of the carcinogenic compounds 5‐methylchrysene‐5‐^14^C, 2‐methylaniline‐methyl‐^14^C and 3‐methyl‐2‐naphthyl‐amine‐methyl‐^14^C. In each case, label was introduced with ^14^CO~2~ and yields were acceptable for preparation of these compounds for metabolic studies.

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