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A structural analysis ofin vitrocatalytic activities of hammerhead ribozymes

✍ Scribed by Yu Shao; Susan Wu; Chi Yu Chan; Jessie R Klapper; Erasmus Schneider; Ye Ding


Book ID
115001023
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
395 KB
Volume
8
Category
Article
ISSN
1471-2105

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Cleavage activity of a hammerhead ribozy
✍ Fabienne Burlina; Jean-Louis Fourrey; ValΓ©rie Lefort; Alain Favre πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 317 KB

The effects of the introduction of 2',5'-phosphodiester linkages within a hammerhead ribozyme domain have been examined in order to determine the regions which can be modified without impairing the cleavage activity and whether a substrate analogue, containing a 2',5'-linkage at the scissile positio