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A Straightforward Entry to 7-Azabicyclo[2.2.1]heptane-1-carbonitriles in the Synthesis of Novel Epibatidine Analogues

✍ Scribed by Thomas Heugebaert; Joke Van Hevele; Wouter Couck; Vicky Bruggeman; Sarah Van der Jeught; Kurt Masschelein; Christian V. Stevens

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
179 KB
Volume
2010
Category
Article
ISSN
1434-193X

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πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Chemistry in the Am
ChemInform Abstract: Chemistry in the Ambient Field of the Alkaloid Epibatidine. Part 1. 2-(Het)aryl-substituted 7-Azabicyclo[2.2.1]heptane Systems.
✍ A. OTTEN; J. C. NAMYSLO; M. STOERMER; D. E. KAUFMANN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

ChemInform Abstract: New Synthesis of 7-
ChemInform Abstract: New Synthesis of 7-(tert-Butoxycarbonyl)-7-azabicyclo[2.2.1]hept-2-ene. A Key Intermediate in the Synthesis of Epibatidine and Analogues.
✍ L. E. BRIEADDY; F. LIANG; P. ABRAHAM; J. R. LEE; F. I. CARROLL πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 1 views

New Synthesis of 7-(tert-Butoxycarbonyl)-7-azabicyclo[2.2.1]hept-2-ene. A Key Intermediate in the Synthesis of Epibatidine and Analogues. -In continuation of efforts on efficient synthetic routes to the alkaloid epibatidine (V), an improved procedure for the synthesis of the N-Boc protected azabicy

ChemInform Abstract: A New [4 + 2] Cyclo
ChemInform Abstract: A New [4 + 2] Cycloaddition Strategy for the Synthesis of N-Acyl-7-azabicyclo[2.2.1]heptan-2-ones: A Formal Synthesis of (.+-.)-Epibatidine.
✍ M. L. TRUDELL; N. P. PAVRI πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 36 KB πŸ‘ 2 views

A New [4 + 2] Cycloaddition Strategy for the Synthesis of N-Acyl-7-azabicyclo[2.2.1]heptan-2-ones: A Formal Synthesis of (Β±)-Epibatidine. -The title compound (VIII), an intermediate for the preparation of (Β±)-epibatidine, is prepared via Diels-Alder reaction of allenes with N-acylated pyrrole (II)