ChemInform Abstract: Efficient Synthesis of (.+-.)-N-Boc-exo-2-(methoxycarbonyl)-7- azabicyclo(2.2.1)heptane, a Versatile Intermediate for the Synthesis of Epibatidine and Epiboxidine.
โ Scribed by S. SINGH; G. P. BASMADJIAN
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
A New [4 + 2] Cycloaddition Strategy for the Synthesis of N-Acyl-7-azabicyclo[2.2.1]heptan-2-ones: A Formal Synthesis of (ยฑ)-Epibatidine. -The title compound (VIII), an intermediate for the preparation of (ยฑ)-epibatidine, is prepared via Diels-Alder reaction of allenes with N-acylated pyrrole (II)
New Synthesis of 7-(tert-Butoxycarbonyl)-7-azabicyclo[2.2.1]hept-2-ene. A Key Intermediate in the Synthesis of Epibatidine and Analogues. -In continuation of efforts on efficient synthetic routes to the alkaloid epibatidine (V), an improved procedure for the synthesis of the N-Boc protected azabicy