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A spectrophotometric assay for determining the rate constants of acetylcholinesterase inhibitions

✍ Scribed by James K. Stoops; Myron L. Bender


Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
625 KB
Volume
63
Category
Article
ISSN
0003-2697

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✦ Synopsis


A spectrophotometric assay procedure has been developed for determining the rate constants for the inhibition of acetylcholinesterase by carbamates and phosphates. The method permits the investigation of inhibitors over a large range in the value of the phosphorylation or carbamylation rate constants without involving the kinetic parameters of the assay substrate in the calculations.


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