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A simple synthesis of a stable thromboxane A2 analogue

โœ Scribed by Paul Barraclough

Publisher
Elsevier Science
Year
1980
Tongue
French
Weight
202 KB
Volume
21
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

A simple synthetic route, which appears to have some general utility, has been used to obtain a Bicyclo[2.2.l]heptane analogue of Thromboxane A2.

Thromboxane A2 (TXA2), an unstable metabolite of arachidonic acid in platelets,

๐Ÿ“œ SIMILAR VOLUMES

Synthesis of structure analogues of thro
Synthesis of structure analogues of thromboxane A2
โœ M.F. Ansell; M.P.L. Caton; M.N. Palfreyman; K.A.J. Stuttle ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 117 KB

AnaloguesI of thromboxane A2 (TXA2) in which the ether linkages are replaced by carbon groupings have been synthesised by elaboration of a connnercially available pinene derivative IIb.