A simple route to (2R,3R,5E)-2-hydroxy-3-methyl-5-heptenal: a key intermediate for (4R)-4-[(E)-2-butenyl]-4,N-dimethyl-L-threonine (MeBmt)
β Scribed by Rao, A. V. Rama; Gurjar, M. K.; Bose, D. S.; Devi, R. Revathi
- Book ID
- 127089523
- Publisher
- American Chemical Society
- Year
- 1991
- Tongue
- English
- Weight
- 289 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
## cis-Oxazolidinone derivative 130) readily real&xl from chiral 2,3-epoxy alcohol (27) h3 been exploited in the synthesis of (4R)-4_i(E~-2-butenyl1-4,N~imethyl-L-threonine f2), an unusual B-hydroxyaamina acid present in cyoiosporin lhe intrirrric feature of this approach involved facile isomerisati
Introduction. ~ Stereoselective C-C bond forming reactions catalyzed by chiral transition-metal complexes are a topic of fundamental importance [l]. In 1986, Hayashi and Zto reported an elegant asymmetric synthesis of dihydrooxazoles by an efficient gold(1)-catalyzed coupling of aldehydes with 2-iso
## Abstract The now corrected Xβray structure of (2__R__)βbornaneβ10,2βsultam ((β)β**1a**), as well as that of its already published __N__βcrotonoyl derivative (β)β**1d**, were compared with those of the newly synthesized (2__R__)βfenchaneβ8,2βsultam ((+)β**5a**), as well as its __N__βcrotonoyl der