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A simple and efficient synthesis of (7E, 9E, 11Z, 13E)-(5S, 6R, 15S)-trihydroxyeicosatetraenoic acid (6R-lipoxin A)

โœ Scribed by E.J. Corey; Wei-guo Su; Martin B. Cleaver


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
253 KB
Volume
30
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


A stereoselective and practical synthesi
โœ E.J. Corey; Mukund M. Mehrotra ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 267 KB

A stereoselective synthesis of 4, a possible biosynthetic precursor of lipoxins, is reported. A pathway is suggested by which 4 can give rise to the biologically active lipoxins 1 and 2. In 1984 Serhan, Hamberg and Samuelsson reported that human leukocytes convert 15(S)-