A role for the polymorphism at position 247 of the β2-glycoprotein I gene in the generation of anti–β2-glycoprotein I antibodies in the antiphospholipid syndrome
✍ Scribed by Naoto Hirose; Roxanne Williams; Alan R. Alberts; Richard A. Furie; Elliot K. Chartash; Rita I. Jain; Cristina Sison; Robert G. Lahita; Joan T. Merrill; Elena Cucurull; Azzudin E. Gharavi; Lisa R. Sammaritano; Jane E. Salmon; Shiori Hashimoto; Tetsuji Sawada; Charles C. Chu; Peter K. Gregersen; Nicholas Chiorazzi
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 185 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0004-3591
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We describe two patients with the catastrophic antiphospholipid syndrome associated with elevation of  2glycoprotein I antibodies and fulminant thrombotic diatheses. Both patients were treated with therapeutic plasma exchange (TPE), which resulted in a marked decrease in antibody titer accompanied