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A report of human herpesvirus 6–associated encephalitis in a solid organ transplant recipient and a review of previously published cases

✍ Scribed by Christopher Vinnard; Todd Barton; Elliot Jerud; Emily Blumberg

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
111 KB
Volume
15
Category
Article
ISSN
1527-6465

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✦ Synopsis

Human herpesvirus 6 (HHV-6) is a common pathogen among children, classically presenting as fever and rash that resolve without specific therapy (exanthem subitum or roseola infantum). Also identified as a pathogen in hematopoietic cell transplant and solid organ transplant (SOT) recipients, it has been recognized as a cause of limbic encephalitis, characterized by confusion and amnesia, with magnetic resonance imaging findings of T2 hyperintensity of the amygdala and hippocampus. We report a case of limbic encephalitis associated with HHV-6 infection in a liver transplant recipient, and we review previously reported cases of HHV-6 encephalitis in SOT recipients.

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