A recurring temperature-sensitive mutant class of BHK-21 cells
β Scribed by Harriet K. Meiss; Antonio Talavera; Takeharu Nishimoto
- Book ID
- 112559749
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 268 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1572-9931
No coin nor oath required. For personal study only.
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## Abstract A temperatureβsensitive growth mutant derived from the BHK 21 cell Line, ts AF8, was found to have greatly reduced DNA synthesis at the nonpermissive temperature. This reduction is mainly due to a decrease in the frequency of cells synthesizing DNA. Upon shift up, ts AF8 becomes blocked
## Abstract Three different temperature sensitive mutants derived from the Syrian hamster cell line BHK 21 were found to have greatly reduced DNA synthesis at the nonβpermissive temperature. These mutants are distinct by complementation analysis and behave at the nonβpermissive temperature as cell