𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A rapid microwave assisted synthesis of [U-14C]isosorbide and dimethyl[U-14C]isosorbide from D-[U-14C]glucose

✍ Scribed by K. M. Mathew; S. Ravi; D. Padmanabhan; V. K. P. Unny; N. Sivaprasad

Publisher
John Wiley and Sons
Year
2006
Tongue
French
Weight
104 KB
Volume
49
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

[U‐^14^C]Isosorbide and [U‐^14^C]dimethyl isosorbide with a specific activity of 462 MBq/mmol was prepared from D‐[U‐^14^C]glucose, in an overall yield of 79%, under microwave heating conditions. Copyright © 2006 John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

Synthesis of glucose 1-phosphate-U-14C a
Synthesis of glucose 1-phosphate-U-14C and specifically labeled sucroses using sucrose phosphorylase
✍ Bruce M. Chassy; Micah I. Krichevsky 📂 Article 📅 1972 🏛 Elsevier Science 🌐 English ⚖ 500 KB

More than twenty years ago Hassid, Doudoroff, and Barker investigated the mechanism of action of sucrose phosphorylase (disaccharide glucosyltransferase (non-specific), EC 2.4.1.7) isolated from Pseudomonas sac-c~a~o~~~~ using radioisotopes (l-3). These classical studies not only led to the postulat

Synthesis of 1-(3,4-dimethylphenyl)-1-[r
Synthesis of 1-(3,4-dimethylphenyl)-1-[ring-U-14C]phenylethane, and of 1-(3,4-dimethylphenyl)-1- phenyl[1-14C]ethane, 14C-labeled distillate of ecoscint-OTM, a biodegradable liquid scintillator
✍ K. Saito; N. Kurihara 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 261 KB

## Abstract 1 ‐(3,4‐Dimethylphenyl)‐ 1 ‐[ring‐U‐^14^C]phenylethane, and 1‐(3,4‐dimethylphenyl)‐ 1‐phenyl[1 ‐ ^14^C]ethane, the ^14^C‐labeled organic solvents of Ecoscint‐O^TM^, a so‐called biodegradable scintillation cocktail, were synthesized by simple two‐step reactions on a milligram scale. [Rin

Synthesis of 1-4′ -ethylphenoxy- 14C (U)
Synthesis of 1-4′ -ethylphenoxy- 14C (U) -6,7 -epoxy- 3,7 -dimethyl-2 -octene. A juvenile hormone analog
✍ J. Kalbfeld; L. J. Hoffman; J. H. Chan; D. A. Hermann 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 French ⚖ 133 KB

## Abstract The preparation of 1‐4′ ethylphenoxy‐ ^14^C(U)‐6, 7‐ epoxy ‐ 3, 7‐dimthyl‐2‐octene (^1^, ^2^) involved a single reaction wherein 4‐ethlphenol‐^14^C(U) (^3^) was mixed with 1‐chloro‐6, 7‐epoxy‐3, 7‐dimithyl‐2‐octene in an acetone water solution at reflux lu‐sing potassium carbonate as a

Synthesis of 13C- and 14C-labeled 1192U9
Synthesis of 13C- and 14C-labeled 1192U90, an ortho-amino benzamide with a preclinical atypical antipsychotic profile
✍ Mark H. Norman; Stephen D. Gabriel 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 571 KB

Three isotopic forms of potential antipsychotic agent 1192U90 (2-amino-N-(4-(4-( 1.2benzisothiazol-3-y1)-1-piperaziny1)butyl)benzamide) were synthesized: one containing 13C-isotopes and two containing l4C-isotopes. The compound in which the ortho-amino benzamide ring is completely %XabeIed was prepa

[U-14C]- and [13C6]-1,3-dibromobenzene;
[U-14C]- and [13C6]-1,3-dibromobenzene; useful precursors with a rare substitution pattern in the synthesis of isotopologs
✍ Jonas Malmquist 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 84 KB

## Abstract A four‐step procedure for the preparation of [U‐^14^C]‐1,3‐dibromobenzene and [^13^C~6~]‐1,3‐dibromobenzene, from the corresponding bromobenzene, has been developed in a 30% yield. The products were isolated in a high specific activity, 2.6 GBq/mmol, and highest possible ^13^C incorpora