A prospective randomized trial of methotrexate versus cisplatin in the treatment of recurrent squamous cell carcinoma of the head and neck
β Scribed by Waun Ki Hong; Steven Schaefer; Brian Issell; Charles Cummings; Daniel Luedke; Richard Bromer; Stephanie Fofonoff; Joan D'Aoust; Stanley Shapshay; Janet Welch; Elizabeth Levin; Miriam Vincent; Charles Vaughan; Stuart Strong
- Book ID
- 111697608
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 412 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0008-543X
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π SIMILAR VOLUMES
Thirty-six patients with squamous cell carcinoma of the head and neck were treated with sequential methotrexate-5-fluorouracil followed by leucovorin rescue. The frequency of objective tumor regression obtained was 64% (complete response + partial response) with 19% complete regression. In 20 not pr
## Abstract ## Objective. We assessed the response rate and the toxicity of cisplatin plus vinorelbine in patients with this condition. ## Patients and Method. Fortyβtwo patients were included. Therapy consisted of cisplatin, 100 mg/m^2^ on day 1, and vinorelbine, 25 mg/m^2^ on days 1 and 8, giv