✦ LIBER ✦

A practical synthesis of peptide mimetics via the solid-phase Petasis reaction

✍ Scribed by Sean R Klopfenstein; Jack J Chen; Adam Golebiowski; Min Li; Sean X Peng; Xia Shao

Publisher: Elsevier Science
Year: 2000
Tongue: French
Weight: 152 KB
Volume: 41
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)00668-7

No coin nor oath required. For personal study only.

✦ Synopsis

The boronic acid Mannich reaction (Petasis reaction) is demonstrated on a solid support. Peptide mimetics are formed from N-alkylated amino acid resin esters, glyoxylic acid and boronic acids.

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