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Solid phase synthesis of β-lactams via the Staudinger reaction

✍ Scribed by Rajinder Singh; John M. Nuss

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
205 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

The synthesis of cis-azetidinones on solid support via the Staudinger reaction is described. The final products are obtained in high purity with no purification required.

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Asymmetric Synthesis of β-Lactams by Sta
Asymmetric Synthesis of β-Lactams by Staudinger Ketene-Imine Cycloaddition Reaction
✍ Claudio Palomo; Jesus M. Aizpurua; Iñaki Ganboa; Mikel Oiarbide 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 886 KB

2 + 2] Cycloaddition reactions between ketenes, bearing known. In this way β-lactams with a widely varying substitution pattern at the C-3 and C-4 positions of the ring amino-, oxy-, or halo-groups, and imines are recognized as being amongst the most important and direct routes to β-are constructed