Here we report the complete nucleotide sequence of a third chitinase gene ( C H T l ) from the dimorphic human pathogen Candida albicans. The deduced amino acid (aa) sequence of Chtl consists of 416 aa and displays 36% protein sequence similarity to chitinases Cht2 and Cht3, from C. albicans. Intere
A phosphatidylinositol 3-kinase of Candida albicans: molecular cloning and characterization
✍ Scribed by Raimund Eck; Astrid Bruckmann; Reinhard Wetzker; Waldemar Künkel
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 378 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0749-503X
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The authors thank the surgeons and operating theater staff and the staff of the Department of Pathology at Western Hospital for their help and cooperation in obtaining tissue for this study.
We have isolated the Candida albicans HIS4 (CaHIS4) gene by complementation of a his4-34 Saccharomyces cerevisiae mutant. The sequenced DNA fragment contains a putative ORF of 2514 bp, whose translation product shares a global identity of 44% and 55% to the His4 protein homologs of S. cerevisiae and
We have cloned and sequenced a Candida albicans gene (SSB1) encoding a potential member of the heat-shock protein seventy (hsp70) family. The protein encoded by this gene contains 613 amino acids and shows a high degree (85%) of sequence identity to the ssb subfamily (ssb1 and ssb2) of the Saccharom