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Molecular cloning of a third chitinase gene (CHT1) from Candida albicans

โœ Scribed by Kenneth J. McCreath; Charles A. Specht; Yilun Liu; Phillips W. Robbins

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
341 KB
Volume
12
Category
Article
ISSN
0749-503X

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โœฆ Synopsis

Here we report the complete nucleotide sequence of a third chitinase gene ( C H T l ) from the dimorphic human pathogen Candida albicans. The deduced amino acid (aa) sequence of Chtl consists of 416 aa and displays 36% protein sequence similarity to chitinases Cht2 and Cht3, from C. albicans. Interestingly the domain structure of Chtl is truncated when compared to the other chitinases of C. albicans and lacks a SerlThr-rich region.:The sequence data will appear in the GenBank Nucleotide Sequence Data Library under the accession number U36490.

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