✦ LIBER ✦

Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors

✍ Scribed by Wayne A. Phillips; Fiona St. Clair; Adam D. Munday; Robert J. S. Thomas; Christina A. Mitchell

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 125 KB
Volume: 83
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19980701)83:1<41::aid-cncr6>3.0.co;2-h

No coin nor oath required. For personal study only.

✦ Synopsis

The authors thank the surgeons and operating theater staff and the staff of the Department of Pathology at Western Hospital for their help and cooperation in obtaining tissue for this study.

📜 SIMILAR VOLUMES

Thrombin-stimulated phosphatidylinositol

Thrombin-stimulated phosphatidylinositol 3-kinase activity in platelets is associated with activation of PYK2 tyrosine kinase: activation of both enzymes is aggregation independent

✍ Mohamed R. Sayed; Michael P. Sheid; Christiaan M. Stevens; Vincent Duronio 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB

In this study, we investigated the activation of a new member of the focal adhesion kinase family of tyrosine kinases, the proline-rich tyrosine kinase, or PYK2, in platelets. We show that PYK2 is tyrosine phosphorylated and its activity is increased during early stages of platelet aggregation. This

Association of PTEN gene methylation wit

Association of PTEN gene methylation with genetic alterations in the phosphatidylinositol 3-kinase/AKT signaling pathway in thyroid tumors

✍ Peng Hou; Meiju Ji; Mingzhao Xing 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB

Activation of phosphatidylinositol 3-kin

Activation of phosphatidylinositol 3-kinase by brain-derived neurotrophic factor gene transfection in septo-hippocampal cultures

✍ Y.H. Qiu; X. Zhao; R.L. Hayes; J.R. Perez-Polo; B.R. Pike; L. Huang; G.L. Clifto 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB 👁 2 views

Brain-derived neurotrophic factor (BDNF) has therapeutic potential for treatment of the injured central nervous system. BDNF induces both differentiation and survival of neurons by binding to trkB receptors. This interaction stimulates the intrinsic tyrosine kinase activity of trkB, initiating a sig

Increases in mRNA levels of glucose tran

Increases in mRNA levels of glucose transporters types 1 and 3 in Ehrlich ascites tumor cells during tumor development

✍ K.K. Au; E. Liong; J.Y. Li; P.S. Li; C.C. Liew; T.T. Kwok; Y.M. Choy; C.Y. Lee; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB

A common feature of many tumors is an increase in glucose catabolism during tumor growth. We studied the mechanism of this phenomenon by using Ehrlich ascites tumor bearing mice as the animal model. We found that Ehrlich ascites tumor cells possess only glucose transporter 1 (GLUT1) and GLUT3 but no

Roles of phosphatidylinositol 3-kinase a

Roles of phosphatidylinositol 3-kinase and phospholipase D in temporal activation of superoxide production in FMLP-stimulated human neutrophils

✍ Kozo Yasui; Atsushi Komiyama 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB

Genetic alterations in the RAS/RAF/mitog

Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma

✍ Libero Santarpia; Jeffrey N. Myers; Steven I. Sherman; Francesco Trimarchi; Gary 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 284 KB

## Abstract ## BACKGROUND: The follicular variant of papillary thyroid carcinoma (FVPTC) is the second most common histotype among papillary thyroid cancers (PTCs). Although the prognosis of FVPTC is similar to the conventional phenotype, differential diagnostic difficulties may not be uncommon wi