Association of PTEN gene methylation with genetic alterations in the phosphatidylinositol 3-kinase/AKT signaling pathway in thyroid tumors

Genetic alterations in the RAS/RAF/mitog

Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma

✍ Libero Santarpia; Jeffrey N. Myers; Steven I. Sherman; Francesco Trimarchi; Gary 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 284 KB

## Abstract ## BACKGROUND: The follicular variant of papillary thyroid carcinoma (FVPTC) is the second most common histotype among papillary thyroid cancers (PTCs). Although the prognosis of FVPTC is similar to the conventional phenotype, differential diagnostic difficulties may not be uncommon wi