A Phase I study of 9-nitrocamptothecin g
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M. Dror Michaelson; David P. Ryan; Charles S. Fuchs; Jeffrey G. Supko; Rocio Gar
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Article
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2002
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John Wiley and Sons
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English
β 83 KB
π 1 views
## Abstract ## BACKGROUND 9βNitrocamptothecin (9βNC) is an orally available camptothecin analog with antineoplastic activity that results from the inhibition of DNA topoisomerase I. Previous studies have suggested that it has significant clinical efficacy. The primary toxicities of 9βNC include ga