## Abstract ## BACKGROUND. Bortezomib is the first proteasome inhibitor to show preliminary evidence of activity against solid tumors. Findings from preclinical studies prompted a Phase I trial to determine the maximum tolerated dose (MTD) and doseβlimiting toxicities (DLTs) of bortezomib in combi
A Phase I study of bortezomib plus irinotecan in patients with advanced solid tumors
β Scribed by David P. Ryan; Bert H. O'Neil; Jeffrey G. Supko; Carlo M. Rocha Lima; E. Claire Dees; Leonard J. Appleman; Jeffrey Clark; Phinos Fidias; Robert Z. Orlowski; Oscar Kashala; Joseph P. Eder; James C. Cusack Jr.
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 278 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
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