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A novel radioligand for imaging the AT1 angiotensin receptor with PET

✍ Scribed by William B Mathews; Sung-Eun Yoo; Sung-Hou Lee; Ursula Scheffel; Paige A Rauseo; Tamas G Zober; Gerard Gocco; Kathryn Sandberg; Hayden T Ravert; Robert F Dannals; Zsolt Szabo


Book ID
116798734
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
95 KB
Volume
31
Category
Article
ISSN
0969-8051

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The renin‐angiotensin system regulates blood pressure via activation of the angiotensin II type 1 receptor (AT~1~R). The AT~1~R is involved in the pathology of cardiac and renal diseases such as heart failure and diabetic nephropathy. The aim of this study was to synthesize and characterize the O‐[^