๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A Novel Nicotinic Acetylcholine Receptor Antagonist Radioligand for PET Studies.

โœ Scribed by Yu-Shin Ding; Kun-eek Kil; Kuo-Shyan Lin; Wei Ma; Yasuno Yokota; Ivy F. Carroll

Publisher
John Wiley and Sons
Year
2006
Weight
16 KB
Volume
37
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

[3H]imidacloprid: Synthesis of a candida
[3H]imidacloprid: Synthesis of a candidate radioligand for the nicotinic acetylcholine receptor
โœ Bachir Latli; John E. Casida ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 192 KB

## Abstract Imidacloprid is an exceptionally potent insecticide known from physiological studies to act at the nicotinic acetylcholine receptor. To prepare [^3^H]imidacloprid as a candidate radioligand, 6โ€chloronicotinoyl chloride was reduced with NaB^2^H~4~ (in model studies) or NaB^3^H~4~ in abso

An HPLC assay for the norditerpenoid alk
An HPLC assay for the norditerpenoid alkaloid methyllycaconitine, a potent nicotinic acetylcholine receptor antagonist
โœ Philippa A. Coates; Ian S. Blagbrough; Terence Lewis; Barry V.L. Potter; Michael ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 280 KB

The extremely potent and selective nicotinic acctylcholine receptor antagonist mcthyllycaconitinc, M LA, and related norditerpenc alkaloids arc finding increasing use as neurochcmical probes and as targets for structure-activity relationship stutlics. In this work, an assay procedure for MLA which u

Synthesis of [18F]3-[1-(3-fluoropropyl)-
Synthesis of [18F]3-[1-(3-fluoropropyl)-(S)-pyrrolidin-2-ylmethoxy]pyridine ([18F]NicFP): a potential ฮฑ4ฮฒ2 nicotinic acetylcholine receptor radioligand for PET
โœ Filip Dumont; Abida Sultana; Andrew Balter; Rikki N. Waterhouse ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 102 KB

Nicotinic acetylcholine receptors are widely distributed throughout the human brain and are believed to play a role in several neurological and psychiatric disorders. In order to identify an effective PET radioligand for in vivo assessment of the a4b2 subtype of nicotinic receptor, we synthesized [

Synthesis of 6-chloro-3-((2-(S)-azetidin
Synthesis of 6-chloro-3-((2-(S)-azetidinyl)methoxy)-5-(2-[18F]fluoropyridin-4-yl)pyridine ([18F]NIDA 522131), a novel potential radioligand for studying extrathalamic nicotinic acetylcholine receptors by PET
โœ Yi Zhang; Andrew G. Horti ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 99 KB

## Abstract 6โ€Chloroโ€3โ€((2โ€(__S__)โ€azetidinyl)methoxy)โ€5โ€(2โ€[^18^F]fluoropyridinโ€4โ€yl)pyridine ([^18^F]NIDA 522131), a potential radioligand for studying extrathalamic nicotinic acetylcholine receptors by positronโ€emission tomography, was synthesized via noโ€carrierโ€added nucleophilic [^18^F]fluorin