## Abstract Capillary isoelectric focusing (CIEF) is a common choice for separation and analysis of the charge variants and impurities of therapeutic proteins. In this study, we developed a sensitive CIEF analysis method for determining the charge heterogeneity of therapeutic monoclonal antibody (m
A novel method for quantitative measurement of a biomarker in the presence of a therapeutic monoclonal antibody directed against the biomarker
β Scribed by R. Aleks Davis; Anthony M. Butterfield; Robert J. Konrad; James S. Bourdage
- Book ID
- 108189564
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 382 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0731-7085
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The bicyclic anhydride of DTPA-1-14C (BADTPA-1-14C) was synthesized and reacted with an antibody to human melanoma associated antigen (MAA) and with one to human class II major histocompatibility complex antigen (HLA-DR). DTPA-1-C incorporation per mole of anti MAA at molar ratios of 1:1 to 200:1 ra
A spectrophotometric method for the quantitative determination of the toxic amino acid hypoglycin A in mixtures with leucine is reported. Hypoglycin A is the hypoglycemic principle found in the arilli of the fruit of Highia sapidu (ackee).
A simple assay for protein in the presence of Percoll which requires neither additional instrumentation nor manipulation of the sample is proposed. The method is based on monitoring the absorbance at 750 and 420 nm of color deveioped by protein plus Percoll with Folin-Ciocalteu reagent. Protein can
## Abstract Serological tests for EpsteinβBarr virus (EBV) have been used for many years as diagnostic predictors of nasopharyngeal carcinoma. It has been shown previously that the conventional immunofluorescence assay has a limited diagnostic value, especially in young patients from North African