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A Novel Carrier for the Solid Phase Synthesis of Oligomers

✍ Scribed by Dr. Hubert Köster; Dipl.-Chem. Stephan Geussenhainer


Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
221 KB
Volume
11
Category
Article
ISSN
0044-8249

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📜 SIMILAR VOLUMES


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with K-selectride to afford the desired hydroxy compound 24. Desilylation of 24 with HF ' py gave the hydroxy oxime 25. The C=N bond of 25 was reduced with NaBH,CN providing the desired product 26 together with its C4 epimer.[131 Finally, chromatographically purified 26 was deprotected to the target

A Facile Solid-Phase Strategy for the Sy
✍ Lorenzo De Napoli; Stefania De Luca; Giovanni Di Fabio; Anna Messere; Daniela Mo 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 2 views

A convenient solid-phase synthesis of oligonucleotides conjugated at the 3Ј-end with a tetraphenylporphyrin residue, by means of a new polymeric support bearing as a linker a lysine derivative, has been developed. A porphyrin linked