𝔖 Bobbio Scriptorium
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A Novel Asymmetric Total Synthesis of (+)-Artemisinin

✍ Scribed by Constantino, Mauricio Gomes; Beltrame, Milton; da Silva, Gil Valdo José; Zukerman-Schpector, Julio


Book ID
120486678
Publisher
Taylor and Francis Group
Year
1996
Tongue
English
Weight
432 KB
Volume
26
Category
Article
ISSN
0039-7911

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📜 SIMILAR VOLUMES


Stereoselective total synthesis of (+)-a
✍ J.S Yadav; R Satheesh Babu; G Sabitha 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 163 KB

The total synthesis of the novel antimalarial drug, a sesquiterpene endoperoxide, (+)-artemisinin is described. The approach is flexible and stereoselective. The use of an intermolecular radical reaction on an intermediate iodolactone and a Wittig reaction on a ketone were employed for the synthesis