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A novel asymmetric synthesis of 2-azetidinones from achiral precursors

โœ Scribed by Feng Zhou; Michael R. Detty; Rene J. Lachicotte


Book ID
108387292
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
245 KB
Volume
40
Category
Article
ISSN
0040-4039

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Ahstractz The acctyknii alcohol, 3, readily prepared in two steps from propargyl bromide. 1. is converted to ethyl 2dcoxy-D-xy1ofuTan0side. l3, and to the unnamml L-cnantiomer. 12, in 5 steps and 50% overall yield, utilizing asymmetrk dihydroxylation (AD) of alkcne 7 for intro&&m df chMity. A simila