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A novel approach to simulate gene-environment interactions in complex diseases

✍ Scribed by Roberto Amato; Michele Pinelli; Daniel D'Andrea; Gennaro Miele; Mario Nicodemi; Giancarlo Raiconi; Sergio Cocozza


Book ID
114999365
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
722 KB
Volume
11
Category
Article
ISSN
1471-2105

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For complex diseases, the relationship between genotypes, environment factors, and phenotype is usually complex and nonlinear. Our understanding of the genetic architecture of diseases has considerably increased over the last years. However, both conceptually and methodologically, detecting gene-gen