𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Combinatorial Approach to Detecting Gene-Gene and Gene-Environment Interactions in Family Studies

✍ Scribed by Xiang-Yang Lou; Guo-Bo Chen; Lei Yan; Jennie Z. Ma; Jamie E. Mangold; Jun Zhu; Robert C. Elston; Ming D. Li


Book ID
113422533
Publisher
American Society of Human Genetics
Year
2008
Tongue
English
Weight
350 KB
Volume
83
Category
Article
ISSN
0002-9297

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


SVM-Based Generalized Multifactor Dimens
✍ Yao-Hwei Fang; Yen-Feng Chiu πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons 🌐 English βš– 615 KB

Gene‐gene interaction plays an important role in the etiology of complex diseases, which may exist without a genetic main effect. Most current statistical approaches, however, focus on assessing an interaction effect in the presence of the gene's main effects. It would be very helpful to develop met

Detecting gene-environment interactions
✍ Alisa M. Goldstein; Roni T. Falk; Jeannette F. Korczak; Jay H. Lubin πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 61 KB πŸ‘ 1 views

We assessed the sample size required for detecting gene-environment (G Γ— E) interactions in a case-control study of complex diseases. The results suggest that large numbers of cases and controls will be required to detect G Γ— E interaction for some odds ratio and exposure frequency combinations. The

Detecting gene-environment interactions
✍ Corinne D. Engelman; James W. Baurley; Yen-Feng Chiu; Bonnie R. Joubert; Juan P. πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 93 KB πŸ‘ 2 views

## Abstract Despite the importance of gene‐environment (GΓ—E) interactions in the etiology of common diseases, little work has been done to develop methods for detecting these types of interactions in genome‐wide association study data. This was the focus of Genetic Analysis Workshop 16 Group 10 con

Entropy-based information gain approache
✍ R. Fan; M. Zhong; S. Wang; Y. Zhang; A. Andrew; M. Karagas; H. Chen; C.I. Amos; πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 259 KB πŸ‘ 2 views

For complex diseases, the relationship between genotypes, environment factors, and phenotype is usually complex and nonlinear. Our understanding of the genetic architecture of diseases has considerably increased over the last years. However, both conceptually and methodologically, detecting gene-gen