## Abstract Despite tremendous efforts, few genes involved in the susceptibility for complex disorders have been identified. One explanation is that these disorders are a result of an interaction between genes and environment, and under such conditions, it may be difficult to measure the true genet
✦ LIBER ✦
Parent–child pair design for detecting gene–environment interactions in complex diseases
✍ Scribed by Yuan-De Tan; Myriam Fornage; Varghese George; Hongyan Xu
- Book ID
- 106134557
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 500 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0340-6717
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## Abstract Estimation and testing of genetic effects (genotype relative risks) are often performed conditionally on parental genotypes, using data from case‐parent trios. This strategy avoids having to estimate nuisance parameters such as parental mating type frequencies, and also avoids generatin