A new synthesis of (±)-sarkomycin from a β-ketophosphonate
✍ Scribed by Marian Mikołajczyk; Remigiusz Zurawiński; Piotr Kiełbasiński
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 200 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A concise route to a new β‐ketophosphonate analog of glycosyl nucleotides is described. Such a diphosphate bioisostere is a stable mimic of enzyme substrates involved in peptidoglycan biosynthesis and will be the starting point for the development of new potential antibiotics. The synth
## Abstract For Abstract see ChemInform Abstract in Full Text.
Enol phosphates, readfly prepared from ketone enolates and dfalkyl phosphorochlorfdate, can be converted to the analogous 6-ketophosphonates by treatment wfth strong base.