Akfrad: A novel total synthesis of oxanosinc has been dcvclopcd. The key hctcrocyclc forming reaction of this synthesis is the carbodiimidc mediated dehydration and cyclization of an urea-acid derived from AICA-riboside. The same procedure was also applied to the synthesis of I-thiaguanosine. Oxano
A new synthesis of oxanosine and 2′-deoxyoxanosine
✍ Scribed by Lorenzo De Napoli; Giovanni Di Fabio; Anna Messere; Daniela Montesarchio; Gennaro Piccialli; Michela Varra
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 219 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
An easy and more efficient synthesis of oxanosine and 2'-deoxyoxanosine has been developed, a key step in the reported synthesis is a new photochemical transformation by UV irradiation of 1-hydroxy derivatives of inosine.
📜 SIMILAR VOLUMES
The total synthesis of oxanosine, a novel nucleoside antibiotic, has been achieved for the first time. Oxanosine ( ) is a novel nucleoside antibiotic isolated from the culture filtrate of Streptomyces capreolus MG265-CF3. 1 The structure was determined to be 5-amino-3-p-D-ribofurano-
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.