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A new synthesis and NMR-spectroscopy of [15N-, 5,4-13C]-aminolevulinic acid

✍ Scribed by Bernhard Nitsche; Hans-Peter Köst; Edmund Cmiel; Siegfried Schneider


Publisher
John Wiley and Sons
Year
1987
Tongue
French
Weight
264 KB
Volume
24
Category
Article
ISSN
0022-2135

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✦ Synopsis


A new synthesis of i' 5N-, 5,4-13C1-aminolevulinic acid (ALA) starting from amorphous 13C is described. NMR-spectroscopic data ( HI 13C, 15N) of the product are presented.


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Synthesis of 13C and 15N multilabeled 5-
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## Abstract ^15^N NMR chemical shifts of 2‐aryl‐1,3,4‐oxadiazoles were assigned on the basis of the ^1^H–^15^N HMBC experiment. Chemical shifts of the nitrogen and carbon atoms in the oxadiazole ring correlate with the Hammett σ‐constants of substituents in the aryl ring (__r__^2^ ≥ 0.966 for N ato