A novel and efficient synthesis of the n
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Ji-Wang Chern; Leroy B. Townsend
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Article
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1985
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Elsevier Science
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French
⚖ 264 KB
1-Methylisoguanosine was synthesized by a one-pot reaction involving a condensation of 5-amino-l-(L3-D-ribofuranosyl)imidazole-4-carboxamide (1) with methyl isothiocyanate, treatment of the resulting thiourea derivative with DCC furnished 5-(3-methyl-1-ureidol-l-(&gribofuranosyl)imidazole-4-carbonit