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A new heterocyclic compound 3,3a-dihydro-2H,9H-isoxazolo[3,2-b][1,3]benzoxazin-9-one

โœ Scribed by D. B. Reisner; B. J. Ludwig


Book ID
112122046
Publisher
Journal of Heterocyclic Chemistry
Year
1969
Tongue
English
Weight
94 KB
Volume
6
Category
Article
ISSN
0022-152X

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๐Ÿ“œ SIMILAR VOLUMES


Absorption, distribution, and metabolic
โœ Jerome Edelson; J. F. Douglas; B. J. Ludwig ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 441 KB

The absorption. distribution, and metabolic fate of seclazone was studied in the rat, dog, and rhesus monkey. Seclazone is readily absorbed by all species. The half-life of blood radioactivity following oral administration of seclazone-9J4C was 10.8.5, and 6 hr. in the rat, beagle hound, and rhesus

Absorption, distribution, and metabolic
โœ Jerome Edelson; J. F. Douglas; B. J. Ludwig; E. B. Schuster; S. Shahinian ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 581 KB

The absorption and metabolic fate of 7-chloro-3,3adihydro-2-methyl-2H,9H-isoxazolo-(3,2-b)( 1,3)-benzoxazin-9-one (I) was studied in rats, dogs, and humans. Orally administered I was readily absorbed by all species. In the rat, orally administered I was converted to its metabolite, 5-chlorosalicylic