The absorption. distribution, and metabolic fate of seclazone was studied in the rat, dog, and rhesus monkey. Seclazone is readily absorbed by all species. The half-life of blood radioactivity following oral administration of seclazone-9J4C was 10.8.5, and 6 hr. in the rat, beagle hound, and rhesus
Comparative anti-inflammatory, analgesic, and antipyretic activities of 7-chloro-3,3a-dihydro-2-methyl-2H,9H-isoxazolo-(3,2-b)(1,3)-benzoxazin-9-one and 5-chlorosalicylic acid in rats
β Scribed by R. D. Sofia; W. Diamantis; B. J. Ludwig
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 490 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3549
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π SIMILAR VOLUMES
A simple, rapid, and quantitative NMR method was developed for the determination of the ratio of the diastereoisomers present in 7-chloro-3,3a-dihydro-2-methyl-2H, 9H-isoxazolo(3,2-b)(1,3)benzoxazin-9-one (I). Deuterated tris(1,1,1,2,2,3,3heptafluoro-7,7-dimethyl-4,6-octanedionato)europium I11 shift
## Abstract The title compounds **6**, **8** and **10**, which are dihydroarene sulfides of the environmental pollutants triphenylene, benzo[__b__]fluorene and benzo[__k__]fluoranthene, have been synthesized from the corresponding epoxides and __N,N__βdimethylthioformamide. The mutagenicity of the