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A new general synthetic route to bridged carboxylic ortho esters

✍ Scribed by E.J. Corey; Natarajan Raju


Publisher
Elsevier Science
Year
1983
Tongue
French
Weight
216 KB
Volume
24
Category
Article
ISSN
0040-4039

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A new general synthetic route to bridged
✍ E.J. Corey; Natarajan Raju πŸ“‚ Article πŸ“… 1983 πŸ› Elsevier Science 🌐 French βš– 216 KB

Acylation of the readily available 3-methyl-3-hydroxymethyl oxetane Q leads to the corresponding oxetane esters (3 which rearrange smoothly in the presence of boron trifluoride etherate in methylene chloride at -15" to form ortho esters of the 2,6,7-trioxabicyclo[2.2. aloctane series (2). Protectio

A novel general route to the synthesis o
✍ K. Sucheta; G.S.R. Reddy; D. Ravi; N. Rama Rao πŸ“‚ Article πŸ“… 1994 πŸ› Elsevier Science 🌐 French βš– 135 KB

Carboxylic acids were conveniently esterfied with alcohols and thiols by the use of triphenylphosphine and N-bromo/Iodo succinimide to afford the corresponding esters and thiol esters. Conversion of carboxylic acids to their corresponding esters and thiol esters is a well established fundamental org